Upregulation of Cyclooxygenase-2/Prostaglandin E(2) (COX-2/PGE(2)) Pathway Member Multiple Drug Resistance-Associated Protein 4 (MRP4) and Downregulation of Prostaglandin Transporter (PGT) and 15-Prostaglandin Dehydrogenase (15-PGDH) in Triple-Negative Breast Cancer

Elevated levels of cyclooxygenase-2 (COX-2) and prostaglandin E(2) (PGE(2)) are indicators of a poor prognosis in breast cancer. Using several independent publicly available breast cancer gene expression databases, we investigated other members of the PGE(2) pathway. PGE(2) is produced by COX-2 and...

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Detalles Bibliográficos
Autores principales: Kochel, Tyler J., Goloubeva, Olga G., Fulton, Amy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881873/
https://www.ncbi.nlm.nih.gov/pubmed/27257388
http://dx.doi.org/10.4137/BCBCR.S38529

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