Cargando…

A Cytoplasmic Form of Gaussia luciferase Provides a Highly Sensitive Test for Cytotoxicity

The elimination of unfavorable chemicals from our environment and commercial products requires a sensitive and high-throughput in vitro assay system for drug-induced hepatotoxicity. Some previous methods for evaluating hepatotoxicity measure the amounts of cytoplasmic enzymes secreted from damaged c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsuji, Saori, Ohbayashi, Tetsuya, Yamakage, Kohji, Oshimura, Mitsuo, Tada, Masako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881903/ https://www.ncbi.nlm.nih.gov/pubmed/27228203 http://dx.doi.org/10.1371/journal.pone.0156202

Ejemplares similares

In Vivo Imaging of Ligand Receptor Binding with Gaussia Luciferase Complementation
por: Luker, Kathryn E., et al.
Publicado: (2011)

Functional multiplex reporter assay using tagged Gaussia luciferase
por: van Rijn, Sjoerd, et al.
Publicado: (2013)

Gaussia Luciferase as a Reporter for Quorum Sensing in Staphylococcus aureus
por: Blower, Isobel, et al.
Publicado: (2020)

Dual-Color Fluorescence Imaging to Monitor CYP3A4 and CYP3A7 Expression in Human Hepatic Carcinoma HepG2 and HepaRG Cells
por: Tsuji, Saori, et al.
Publicado: (2014)

Application of Gaussia luciferase in bicistronic and non-conventional secretion reporter constructs
por: Luft, Christin, et al.
Publicado: (2014)

Imaging Tumor Vascularity and Response to Anti-Angiogenic Therapy Using Gaussia Luciferase
por: Kantar, Rami S., et al.
Publicado: (2016)

Truncated Variants of Gaussia Luciferase with Tyrosine Linker for Site-Specific Bioconjugate Applications
por: Hunt, Eric A., et al.
Publicado: (2016)

Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry
por: Wider, Diana, et al.
Publicado: (2017)

A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase
por: Tóth, András Dávid, et al.
Publicado: (2021)

Development of a highly sensitive Gaussia luciferase immunoprecipitation assay for the detection of antibodies against African swine fever virus
por: Ding, Jingjing, et al.
Publicado: (2022)

Secreted Gaussia Luciferase as a Biomarker for Monitoring Tumor Progression and Treatment Response of Systemic Metastases
por: Chung, Euiheon, et al.
Publicado: (2009)

Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout
por: Gläsker, Sabine, et al.
Publicado: (2013)

Easy detection of hormone secretion from LβT2 cells by using Gaussia luciferase
por: SATOU, Kazuhiro, et al.
Publicado: (2017)

A reporter system for assaying influenza virus RNP functionality based on secreted Gaussia luciferase activity
por: Zhu, Wenfei, et al.
Publicado: (2011)

Rapid and sensitive large-scale screening of low affinity extracellular receptor protein interactions by using reaction induced inhibition of Gaussia luciferase
por: Galaway, Francis, et al.
Publicado: (2020)

Continuous long-term cytotoxicity monitoring in 3D spheroids of beetle luciferase-expressing hepatocytes by nondestructive bioluminescence measurement
por: Yasunaga, Mayu, et al.
Publicado: (2017)

A Simple and Robust Approach for Evaluation of Antivirals Using a Recombinant Influenza Virus Expressing Gaussia Luciferase
por: Li, Ping, et al.
Publicado: (2018)

Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase
por: Wang, Lin, et al.
Publicado: (2019)

Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo
por: Wires, Emily S., et al.
Publicado: (2017)

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles
por: Zaborowski, Mikołaj Piotr, et al.
Publicado: (2019)

Development of recombinant rabies viruses vectors with Gaussia luciferase reporter based on Chinese vaccine strain CTN181
por: Du, Jialiang, et al.
Publicado: (2011)

A Recombinant Porcine Reproductive and Respiratory Syndrome Virus Stably Expressing a Gaussia Luciferase for Antiviral Drug Screening Assay and Luciferase-Based Neutralization Assay
por: Li, Yanhua, et al.
Publicado: (2022)

A Gaussia Luciferase Cell-Based System to Assess the Infection of Cell Culture- and Serum-Derived Hepatitis C Virus
por: Koutsoudakis, George, et al.
Publicado: (2012)

Secreted Gaussia princeps Luciferase as a Reporter of Escherichia coli Replication in a Mouse Tissue Cage Model of Infection
por: Liu, Mingyu, et al.
Publicado: (2014)

Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR
por: Wu, Nan, et al.
Publicado: (2020)

A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer
por: Liu, Yang, et al.
Publicado: (2023)

A codon-optimized luciferase from Gaussia princeps facilitates the in vivo monitoring of gene expression in the model alga Chlamydomonas reinhardtii
por: Shao, Ning, et al.
Publicado: (2008)

Listeria innocua Dps as a nanoplatform for bioluminescence based photodynamic therapy utilizing Gaussia princeps luciferase and zinc protoporphyrin IX
por: Al-Ani, Ali W., et al.
Publicado: (2019)

Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression
por: Puckette, Michael, et al.
Publicado: (2017)

Targeted Bioluminescent Imaging of Pancreatic Ductal Adenocarcinoma Using Nanocarrier-Complexed EGFR-Binding Affibody–Gaussia Luciferase Fusion Protein
por: Hersh, Jessica, et al.
Publicado: (2023)

Real‐time fluorometric evaluation of hepatoblast proliferation in vivo and in vitro using the expression of CYP3A7 coding for human fetus‐specific P450
por: Okuyama, Shota, et al.
Publicado: (2020)

Influenza A Virus Encoding Secreted Gaussia Luciferase as Useful Tool to Analyze Viral Replication and Its Inhibition by Antiviral Compounds and Cellular Proteins
por: Eckert, Nadine, et al.
Publicado: (2014)

Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs
por: Li, Feng, et al.
Publicado: (2016)

A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection
por: Li, Chenxi, et al.
Publicado: (2022)

A Method for Producing Transgenic Cells Using a Multi-Integrase System on a Human Artificial Chromosome Vector
por: Yamaguchi, Shigeyuki, et al.
Publicado: (2011)

A kidney injury molecule‐1 (Kim‐1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells
por: Kokura, Kenji, et al.
Publicado: (2016)

Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9
por: Honma, Kazuhisa, et al.
Publicado: (2018)

Hiroshima Symposium on Elementary Excitations in Quantum Fluids
por: Ohbayashi, Kohji, et al.
Publicado: (1989)

Vectors Encoding Seven Oikosin Signal Peptides Transfected into CHO Cells Differ Greatly in Mediating Gaussia luciferase and Human Endostatin Production although mRNA Levels are Largely Unaffected
por: Tröße, Christiane, et al.
Publicado: (2007)

Multiple expression cassette exchange via TP901‐1, R4, and Bxb1 integrase systems on a mouse artificial chromosome
por: Tomimatsu, Kosuke, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_q30mbm7o81rpv02lp645u7058p