Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification

A temporal study of gene expression in peripheral blood leukocytes (PBLs) from a Mycobacterium tuberculosis primary, pulmonary challenge model Macaca fascicularis has been conducted. PBL samples were taken prior to challenge and at one, two, four and six weeks post-challenge and labelled, purified R...

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Detalles Bibliográficos
Autores principales: Javed, Sajid, Marsay, Leanne, Wareham, Alice, Lewandowski, Kuiama S., Williams, Ann, Dennis, Michael J., Sharpe, Sally, Vipond, Richard, Silman, Nigel, Ball, Graham, Kempsell, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882019/
https://www.ncbi.nlm.nih.gov/pubmed/27228113
http://dx.doi.org/10.1371/journal.pone.0154320

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