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An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity
Telomeres are capped at the ends of eukaryotic chromosomes and are composed of TTAGGG repeats bound to the shelterin complex. Here we report that a replication-dependent histone H2A isotype, H2ac, was associated with telomeres in human cells and co-immunoprecipitates with telomere repeat factor 2 (T...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882029/ https://www.ncbi.nlm.nih.gov/pubmed/27228173 http://dx.doi.org/10.1371/journal.pone.0156378 |