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Stoichiometry and Affinity of Thioflavin T Binding to Sup35p Amyloid Fibrils

In this work two modes of binding of the fluorescent probe thioflavin T to yeast prion protein Sup35p amyloid fibrils were revealed by absorption spectrometry of solutions prepared by equilibrium microdialysis. These binding modes exhibited significant differences in binding affinity and stoichiomet...

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Detalles Bibliográficos
Autores principales:	Sulatskaya, Anna I., Kuznetsova, Irina M., Belousov, Mikhail V., Bondarev, Stanislav A., Zhouravleva, Galina A., Turoverov, Konstantin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882037/ https://www.ncbi.nlm.nih.gov/pubmed/27228180 http://dx.doi.org/10.1371/journal.pone.0156314

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