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Effects of Subretinal Gene Transfer at Different Time Points in a Mouse Model of Retinal Degeneration

Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is necessary for photoreceptors to generate an important lipid component of their membranes. The absence of LPCAT1 results in early and rapid rod and cone degeneration. Retinal degeneration 11 (rd11) mice carry a mutation in the Lpcat1 gene, and are...

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Detalles Bibliográficos
Autores principales:	Dai, Xufeng, Zhang, Hua, Han, Juanjuan, He, Ying, Zhang, Yangyang, Qi, Yan, Pang, Ji-jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882044/ https://www.ncbi.nlm.nih.gov/pubmed/27228218 http://dx.doi.org/10.1371/journal.pone.0156542

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