Cargando…
Threonine 89 Is an Important Residue of Profilin-1 That Is Phosphorylatable by Protein Kinase A
OBJECTIVE: Dynamic regulation of actin cytoskeleton is at the heart of all actin-based cellular events. In this study, we sought to identify novel post-translational modifications of Profilin-1 (Pfn1), an important regulator of actin polymerization in cells. METHODOLOGY: We performed in vitro protei...
Autores principales: | Gau, David, Veon, William, Zeng, Xuemei, Yates, Nathan, Shroff, Sanjeev G., Koes, David R., Roy, Partha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882052/ https://www.ncbi.nlm.nih.gov/pubmed/27228149 http://dx.doi.org/10.1371/journal.pone.0156313 |
Ejemplares similares
-
Structural characterizations of phosphorylatable residues in transmembrane proteins from Arabidopsis thaliana
por: Xue, Bin, et al.
Publicado: (2013) -
Profilin-1 versus profilin-2: two faces of the same coin?
por: Ding, Zhijie, et al.
Publicado: (2013) -
Vascular endothelial cell-specific disruption of the profilin1 gene leads to severe multiorgan pathology and inflammation causing mortality
por: Allen-Gondringer, Abigail, et al.
Publicado: (2023) -
Non-phosphorylatable mutants of Ser184 lead to incomplete activation of Bax
por: Simonyan, Lilit, et al.
Publicado: (2023) -
Vascular endothelial profilin-1 drives a protumorigenic tumor microenvironment and tumor progression in renal cancer
por: Gau, David, et al.
Publicado: (2023)