Structural insights into inhibition of Lipid I production in bacterial cell wall synthesis

Antibiotic-resistant bacterial infection is a serious threat to public health. Peptidoglycan biosynthesis is a well-established target for antibiotic development. MraY (phospho-MurNAc-pentapeptide translocase) catalyzes the first and an essential membrane step of peptidoglycan biosynthesis. It is co...

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Detalles Bibliográficos
Autores principales: Chung, Ben C., Mashalidis, Ellene H., Tanino, Tetsuya, Kim, Mijung, Matsuda, Akira, Hong, Jiyong, Ichikawa, Satoshi, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882255/
https://www.ncbi.nlm.nih.gov/pubmed/27088606
http://dx.doi.org/10.1038/nature17636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882255/
https://www.ncbi.nlm.nih.gov/pubmed/27088606
http://dx.doi.org/10.1038/nature17636

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