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The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation

Parasitic nematodes manufacture various carbohydrate-linked phosphorylcholine (PCh)-containing molecules, including ES-62, a protein with an N-linked glycan terminally substituted with PCh. The PCh component is biologically important because it is required for immunomodulatory effects. We showed tha...

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Detalles Bibliográficos
Autores principales:	Ahmed, Umul Kulthum, Maller, N. Claire, Iqbal, Asif J., Al-Riyami, Lamyaa, Harnett, William, Raynes, John G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882459/ https://www.ncbi.nlm.nih.gov/pubmed/27044740 http://dx.doi.org/10.1074/jbc.M115.702746

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