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PGE(2) maintains self-renewal of human adult stem cells via EP2-mediated autocrine signaling and its production is regulated by cell-to-cell contact

Mesenchymal stem cells (MSCs) possess unique immunomodulatory abilities. Many studies have elucidated the clinical efficacy and underlying mechanisms of MSCs in immune disorders. Although immunoregulatory factors, such as Prostaglandin E(2) (PGE(2)), and their mechanisms of action on immune cells ha...

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Detalles Bibliográficos
Autores principales: Lee, Byung-Chul, Kim, Hyung-Sik, Shin, Tae-Hoon, Kang, Insung, Lee, Jin Young, Kim, Jae-Jun, Kang, Hyun Kyoung, Seo, Yoojin, Lee, Seunghee, Yu, Kyung-Rok, Choi, Soon Won, Kang, Kyung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882486/
https://www.ncbi.nlm.nih.gov/pubmed/27230257
http://dx.doi.org/10.1038/srep26298