Donor CD47 controls T cell alloresponses and is required for tolerance induction following hepatocyte allotransplantation

CD47-deficient hepatocyte transplantation induces rapid innate immune cell activation and subsequent associated graft loss in syngeneic recipients. However, the role of donor CD47 in regulation of T-cell alloresponses is poorly understood. We addressed this question by assessing OVA-specific immune...

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Detalles Bibliográficos
Autores principales: Zhang, Mingyou, Wang, Hui, Tan, Shulian, Navarro-Alvarez, Nalu, Zheng, Yang, Yang, Yong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882503/
https://www.ncbi.nlm.nih.gov/pubmed/27230788
http://dx.doi.org/10.1038/srep26839

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