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Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

Ribose-5-phosphate isomerase (RPI) belongs to the non-oxidative branch of the pentose phosphate pathway, catalysing the inter-conversion of D-ribose-5-phosphate and D-ribulose-5-phosphate. Trypanosomatids encode a type B RPI, whereas humans have a structurally unrelated type A, making RPIB worthy of...

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Detalles Bibliográficos
Autores principales:	Faria, Joana, Loureiro, Inês, Santarém, Nuno, Cecílio, Pedro, Macedo-Ribeiro, Sandra, Tavares, Joana, Cordeiro-da-Silva, Anabela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882579/ https://www.ncbi.nlm.nih.gov/pubmed/27230471 http://dx.doi.org/10.1038/srep26937

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