The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease

COPD is characterized by persistent airflow limitation, neutrophilia and oxidative stress from endogenous and exogenous insults. Current COPD therapy involving anticholinergics, β(2)-adrenoceptor agonists and/or corticosteroids, do not specifically target oxidative stress, nor do they reduce chronic...

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Detalles Bibliográficos
Autores principales: Han, Bing, Poppinga, Wilfred J., Zuo, Haoxiao, Zuidhof, Annet B., Bos, I. Sophie T., Smit, Marieke, Vogelaar, Pieter, Krenning, Guido, Henning, Robert H., Maarsingh, Harm, Halayko, Andrew J., van Vliet, Bernard, Stienstra, Stef, Graaf, Adrianus Cornelis van der, Meurs, Herman, Schmidt, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882609/
https://www.ncbi.nlm.nih.gov/pubmed/27229886
http://dx.doi.org/10.1038/srep26928

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