Bioorthogonal Chemical Activation of Kinases in Living Systems

[Image: see text] Selective manipulation of protein kinases under living conditions is highly desirable yet extremely challenging, particularly in a gain-of-function fashion. Here we employ our recently developed bioorthogonal cleavage reaction as a general strategy for intracellular activation of i...

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Detalles Bibliográficos
Autores principales: Zhang, Gong, Li, Jie, Xie, Ran, Fan, Xinyuan, Liu, Yanjun, Zheng, Siqi, Ge, Yun, Chen, Peng R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882735/
https://www.ncbi.nlm.nih.gov/pubmed/27280167
http://dx.doi.org/10.1021/acscentsci.6b00024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882735/
https://www.ncbi.nlm.nih.gov/pubmed/27280167
http://dx.doi.org/10.1021/acscentsci.6b00024

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