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Bioorthogonal Chemical Activation of Kinases in Living Systems
[Image: see text] Selective manipulation of protein kinases under living conditions is highly desirable yet extremely challenging, particularly in a gain-of-function fashion. Here we employ our recently developed bioorthogonal cleavage reaction as a general strategy for intracellular activation of i...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882735/ https://www.ncbi.nlm.nih.gov/pubmed/27280167 http://dx.doi.org/10.1021/acscentsci.6b00024 |