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Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
[Image: see text] While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based tra...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882743/ https://www.ncbi.nlm.nih.gov/pubmed/27280164 http://dx.doi.org/10.1021/acscentsci.6b00091 |
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author | Horn, Evan J. Rosen, Brandon R. Baran, Phil S. |
author_facet | Horn, Evan J. Rosen, Brandon R. Baran, Phil S. |
author_sort | Horn, Evan J. |
collection | PubMed |
description | [Image: see text] While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based transformations, such as high functional group tolerance, mild conditions, and innate scalability and sustainability. In this Outlook we highlight illustrative examples of electrochemical reactions in the context of the synthesis of complex molecules, showcasing the intrinsic benefits of electrochemical reactions versus traditional reagent-based approaches. Our hope is that this field will soon see widespread adoption in the synthetic community. |
format | Online Article Text |
id | pubmed-4882743 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-48827432016-06-08 Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method Horn, Evan J. Rosen, Brandon R. Baran, Phil S. ACS Cent Sci [Image: see text] While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based transformations, such as high functional group tolerance, mild conditions, and innate scalability and sustainability. In this Outlook we highlight illustrative examples of electrochemical reactions in the context of the synthesis of complex molecules, showcasing the intrinsic benefits of electrochemical reactions versus traditional reagent-based approaches. Our hope is that this field will soon see widespread adoption in the synthetic community. American Chemical Society 2016-05-05 2016-05-25 /pmc/articles/PMC4882743/ /pubmed/27280164 http://dx.doi.org/10.1021/acscentsci.6b00091 Text en Copyright © 2016 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
spellingShingle | Horn, Evan J. Rosen, Brandon R. Baran, Phil S. Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method |
title | Synthetic Organic Electrochemistry: An Enabling and
Innately Sustainable Method |
title_full | Synthetic Organic Electrochemistry: An Enabling and
Innately Sustainable Method |
title_fullStr | Synthetic Organic Electrochemistry: An Enabling and
Innately Sustainable Method |
title_full_unstemmed | Synthetic Organic Electrochemistry: An Enabling and
Innately Sustainable Method |
title_short | Synthetic Organic Electrochemistry: An Enabling and
Innately Sustainable Method |
title_sort | synthetic organic electrochemistry: an enabling and
innately sustainable method |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882743/ https://www.ncbi.nlm.nih.gov/pubmed/27280164 http://dx.doi.org/10.1021/acscentsci.6b00091 |
work_keys_str_mv | AT hornevanj syntheticorganicelectrochemistryanenablingandinnatelysustainablemethod AT rosenbrandonr syntheticorganicelectrochemistryanenablingandinnatelysustainablemethod AT baranphils syntheticorganicelectrochemistryanenablingandinnatelysustainablemethod |