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Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method

[Image: see text] While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based tra...

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Autores principales: Horn, Evan J., Rosen, Brandon R., Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882743/
https://www.ncbi.nlm.nih.gov/pubmed/27280164
http://dx.doi.org/10.1021/acscentsci.6b00091
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author Horn, Evan J.
Rosen, Brandon R.
Baran, Phil S.
author_facet Horn, Evan J.
Rosen, Brandon R.
Baran, Phil S.
author_sort Horn, Evan J.
collection PubMed
description [Image: see text] While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based transformations, such as high functional group tolerance, mild conditions, and innate scalability and sustainability. In this Outlook we highlight illustrative examples of electrochemical reactions in the context of the synthesis of complex molecules, showcasing the intrinsic benefits of electrochemical reactions versus traditional reagent-based approaches. Our hope is that this field will soon see widespread adoption in the synthetic community.
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spelling pubmed-48827432016-06-08 Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method Horn, Evan J. Rosen, Brandon R. Baran, Phil S. ACS Cent Sci [Image: see text] While preparative electrolysis of organic molecules has been an active area of research over the past century, modern synthetic chemists have generally been reluctant to adopt this technology. In fact, electrochemical methods possess many benefits over traditional reagent-based transformations, such as high functional group tolerance, mild conditions, and innate scalability and sustainability. In this Outlook we highlight illustrative examples of electrochemical reactions in the context of the synthesis of complex molecules, showcasing the intrinsic benefits of electrochemical reactions versus traditional reagent-based approaches. Our hope is that this field will soon see widespread adoption in the synthetic community. American Chemical Society 2016-05-05 2016-05-25 /pmc/articles/PMC4882743/ /pubmed/27280164 http://dx.doi.org/10.1021/acscentsci.6b00091 Text en Copyright © 2016 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Horn, Evan J.
Rosen, Brandon R.
Baran, Phil S.
Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
title Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
title_full Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
title_fullStr Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
title_full_unstemmed Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
title_short Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
title_sort synthetic organic electrochemistry: an enabling and innately sustainable method
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882743/
https://www.ncbi.nlm.nih.gov/pubmed/27280164
http://dx.doi.org/10.1021/acscentsci.6b00091
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