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Selective mode of action of plumbagin through BRCA1 deficient breast cancer stem cells

BACKGROUND: Studies over the past decade and half have identified cancer stem cells (CSCs) to be responsible for tumorigenesis, invasion, sustenance of metastatic disease, radio- and chemo-resistance and tumor relapse. Recent reports have described the plasticity of breast CSCs (BCSCs) to shift betw...

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Detalles Bibliográficos
Autores principales: Somasundaram, Veena, Hemalatha, Sreelatha K, Pal, Krishnendu, Sinha, Sutapa, Nair, Asha S., Mukhopadhyay, Debabrata, Srinivas, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882782/
https://www.ncbi.nlm.nih.gov/pubmed/27229859
http://dx.doi.org/10.1186/s12885-016-2372-4

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