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Selective mode of action of plumbagin through BRCA1 deficient breast cancer stem cells
BACKGROUND: Studies over the past decade and half have identified cancer stem cells (CSCs) to be responsible for tumorigenesis, invasion, sustenance of metastatic disease, radio- and chemo-resistance and tumor relapse. Recent reports have described the plasticity of breast CSCs (BCSCs) to shift betw...
Autores principales: | Somasundaram, Veena, Hemalatha, Sreelatha K, Pal, Krishnendu, Sinha, Sutapa, Nair, Asha S., Mukhopadhyay, Debabrata, Srinivas, Priya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882782/ https://www.ncbi.nlm.nih.gov/pubmed/27229859 http://dx.doi.org/10.1186/s12885-016-2372-4 |
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