Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients

BACKGROUND: Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery. METHODS: We examined the variability of anti-staphylococcal antibody levels across a group of h...

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Detalles Bibliográficos
Autores principales: Moravcova, Sarka, Kyle, Bonnie, Shanahan, Hilary, Giannaris, Savvas, Smith, Andrew, Hamilton-Davies, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882792/
https://www.ncbi.nlm.nih.gov/pubmed/27239299
http://dx.doi.org/10.1186/s13741-016-0039-y
Descripción
Sumario:BACKGROUND: Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery. METHODS: We examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery. RESULTS: Pre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers. CONCLUSIONS: The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.

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