Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients

BACKGROUND: Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery. METHODS: We examined the variability of anti-staphylococcal antibody levels across a group of h...

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Autores principales: Moravcova, Sarka, Kyle, Bonnie, Shanahan, Hilary, Giannaris, Savvas, Smith, Andrew, Hamilton-Davies, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882792/
https://www.ncbi.nlm.nih.gov/pubmed/27239299
http://dx.doi.org/10.1186/s13741-016-0039-y
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author Moravcova, Sarka
Kyle, Bonnie
Shanahan, Hilary
Giannaris, Savvas
Smith, Andrew
Hamilton-Davies, Colin
author_facet Moravcova, Sarka
Kyle, Bonnie
Shanahan, Hilary
Giannaris, Savvas
Smith, Andrew
Hamilton-Davies, Colin
author_sort Moravcova, Sarka
collection PubMed
description BACKGROUND: Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery. METHODS: We examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery. RESULTS: Pre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers. CONCLUSIONS: The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.
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spelling pubmed-48827922016-05-28 Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients Moravcova, Sarka Kyle, Bonnie Shanahan, Hilary Giannaris, Savvas Smith, Andrew Hamilton-Davies, Colin Perioper Med (Lond) Research BACKGROUND: Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery. METHODS: We examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery. RESULTS: Pre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers. CONCLUSIONS: The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation. BioMed Central 2016-05-27 /pmc/articles/PMC4882792/ /pubmed/27239299 http://dx.doi.org/10.1186/s13741-016-0039-y Text en © Moravcova et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Moravcova, Sarka
Kyle, Bonnie
Shanahan, Hilary
Giannaris, Savvas
Smith, Andrew
Hamilton-Davies, Colin
Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
title Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
title_full Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
title_fullStr Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
title_full_unstemmed Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
title_short Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
title_sort variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882792/
https://www.ncbi.nlm.nih.gov/pubmed/27239299
http://dx.doi.org/10.1186/s13741-016-0039-y
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