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Sustained efficacy of artesunate-sulfadoxine-pyrimethamine against Plasmodium falciparum in Yemen and a renewed call for an adjunct single dose primaquine to clear gametocytes
BACKGROUND: In Yemen, artesunate plus sulfadoxine-pyrimethamine (AS + SP) has been used as first-line treatment for uncomplicated falciparum malaria, which accounts for about 99 % of malaria cases. There is evidence that resistance to SP is increasing, with potential negative impact on efficacy, and...
Autores principales: | Atroosh, Wahib M., Al-Mekhlafi, Hesham M., Snounou, Georges, Al-Jasari, Adel, Sady, Hany, Nasr, Nabil A., Lau, Yee-Ling, Surin, Johari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882835/ https://www.ncbi.nlm.nih.gov/pubmed/27234587 http://dx.doi.org/10.1186/s12936-016-1344-0 |
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