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Chronic administration of AMD3100 increases survival and alleviates pathology in SOD1(G93A) mice model of ALS
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease, involving both upper and lower motor neurons. The disease is induced by multifactorial pathologies, and as such, it requires a multifaceted therapeutic approach. CXCR4, a chemokine receptor widely expre...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882847/ https://www.ncbi.nlm.nih.gov/pubmed/27230771 http://dx.doi.org/10.1186/s12974-016-0587-6 |