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Intrathecal Injection of Resveratrol Attenuates Burn Injury Pain by Activating Spinal Sirtuin 1

OBJECTIVE: The present study sought to detect spinal sirtuin 1 (SIRT1) and acetylation of histone H3 (Ac-H3) expression in rats with burn injury pain (BIP model). PROCEDURES AND RESULTS: A BIP model was first established. BIP rats showed lower paw withdrawal threshold (PWT) from day 1, which persist...

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Detalles Bibliográficos
Autores principales: Cheng, Wei, Wang, Jin-Feng, Yang, Cong-Xian, Wu, Liang, Yin, Qin, Liu, He, Fu, Zhi-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883079/
https://www.ncbi.nlm.nih.gov/pubmed/27279707
http://dx.doi.org/10.4103/0973-1296.182167