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Interactions among Lung Cancer Cells, Fibroblasts, and Macrophages in 3D Co-Cultures and the Impact on MMP-1 and VEGF Expression

In vitro cell-based models of lung cancer are frequently employed to study invasion and the mechanisms behind metastasis. However, these models often study only one cell type with two-dimensional (2D) monolayer cell cultures, which do not accurately reflect the complexity of inflammation in vivo. He...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-qing, Kiefl, Rosemarie, Roskopf, Claudia, Tian, Fei, Huber, Rudolf M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883750/
https://www.ncbi.nlm.nih.gov/pubmed/27232698
http://dx.doi.org/10.1371/journal.pone.0156268

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