Inhibition of Nuclear Transport of NF-ĸB p65 by the Salmonella Type III Secretion System Effector SpvD

Salmonella enterica replicates in macrophages through the action of effector proteins translocated across the vacuolar membrane by a type III secretion system (T3SS). Here we show that the SPI-2 T3SS effector SpvD suppresses proinflammatory immune responses. SpvD prevented activation of an NF-ĸB-dep...

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Detalles Bibliográficos
Autores principales: Rolhion, Nathalie, Furniss, R. Christopher D., Grabe, Grzegorz, Ryan, Aindrias, Liu, Mei, Matthews, Sophie A., Holden, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883751/
https://www.ncbi.nlm.nih.gov/pubmed/27232334
http://dx.doi.org/10.1371/journal.ppat.1005653

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