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Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc

Human GLP-1 (glucagon-like peptide-1) can produce a remarkable improvement in glycemic control in patients with type 2 diabetes. However, its clinical benefits are limited by its short half-life, which is less than 2 min because of its small size and rapid enzymatic inactivation by dipeptidyl peptid...

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Detalles Bibliográficos
Autores principales:	Yang, Yi, Chen, Fang, Wan, Deyou, Liu, Yunhui, Yang, Li, Feng, Hongru, Cui, Xinling, Gao, Xin, Song, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883776/ https://www.ncbi.nlm.nih.gov/pubmed/27232339 http://dx.doi.org/10.1371/journal.pone.0156449

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