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The GTPase SPAG-1 orchestrates meiotic program by dictating meiotic resumption and cytoskeleton architecture in mouse oocytes

In mammals, a finite population of oocytes is generated during embryogenesis, and proper oocyte meiotic divisions are crucial for fertility. Sperm-associated antigen 1 (SPAG-1) has been implicated in infertility and tumorigenesis; however, its relevance in cell cycle programs remains rudimentary. He...

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Detalles Bibliográficos
Autores principales: Huang, Chunjie, Wu, Di, Khan, Faheem Ahmed, Jiao, Xiaofei, Guan, Kaifeng, Huo, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884068/
https://www.ncbi.nlm.nih.gov/pubmed/27053660
http://dx.doi.org/10.1091/mbc.E16-02-0132