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Combined changes in Wnt signaling response and contact inhibition induce altered proliferation in radiation-treated intestinal crypts

Curative intervention is possible if colorectal cancer is identified early, underscoring the need to detect the earliest stages of malignant transformation. A candidate biomarker is the expanded proliferative zone observed in crypts before adenoma formation, also found in irradiated crypts. However,...

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Detalles Bibliográficos
Autores principales: Dunn, S.-J., Osborne, J. M., Appleton, P. L., Näthke, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884076/
https://www.ncbi.nlm.nih.gov/pubmed/27053661
http://dx.doi.org/10.1091/mbc.E15-12-0854