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Combined changes in Wnt signaling response and contact inhibition induce altered proliferation in radiation-treated intestinal crypts
Curative intervention is possible if colorectal cancer is identified early, underscoring the need to detect the earliest stages of malignant transformation. A candidate biomarker is the expanded proliferative zone observed in crypts before adenoma formation, also found in irradiated crypts. However,...
Autores principales: | Dunn, S.-J., Osborne, J. M., Appleton, P. L., Näthke, I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884076/ https://www.ncbi.nlm.nih.gov/pubmed/27053661 http://dx.doi.org/10.1091/mbc.E15-12-0854 |
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