Direct neural pathways convey distinct visual information to Drosophila mushroom bodies

Previously, we demonstrated that visual and olfactory associative memories of Drosophila share mushroom body (MB) circuits (Vogt et al., 2014). Unlike for odor representation, the MB circuit for visual information has not been characterized. Here, we show that a small subset of MB Kenyon cells (KCs)...

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Autores principales: Vogt, Katrin, Aso, Yoshinori, Hige, Toshihide, Knapek, Stephan, Ichinose, Toshiharu, Friedrich, Anja B, Turner, Glenn C, Rubin, Gerald M, Tanimoto, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884080/
https://www.ncbi.nlm.nih.gov/pubmed/27083044
http://dx.doi.org/10.7554/eLife.14009
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author Vogt, Katrin
Aso, Yoshinori
Hige, Toshihide
Knapek, Stephan
Ichinose, Toshiharu
Friedrich, Anja B
Turner, Glenn C
Rubin, Gerald M
Tanimoto, Hiromu
author_facet Vogt, Katrin
Aso, Yoshinori
Hige, Toshihide
Knapek, Stephan
Ichinose, Toshiharu
Friedrich, Anja B
Turner, Glenn C
Rubin, Gerald M
Tanimoto, Hiromu
author_sort Vogt, Katrin
collection PubMed
description Previously, we demonstrated that visual and olfactory associative memories of Drosophila share mushroom body (MB) circuits (Vogt et al., 2014). Unlike for odor representation, the MB circuit for visual information has not been characterized. Here, we show that a small subset of MB Kenyon cells (KCs) selectively responds to visual but not olfactory stimulation. The dendrites of these atypical KCs form a ventral accessory calyx (vAC), distinct from the main calyx that receives olfactory input. We identified two types of visual projection neurons (VPNs) directly connecting the optic lobes and the vAC. Strikingly, these VPNs are differentially required for visual memories of color and brightness. The segregation of visual and olfactory domains in the MB allows independent processing of distinct sensory memories and may be a conserved form of sensory representations among insects. DOI: http://dx.doi.org/10.7554/eLife.14009.001
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spelling pubmed-48840802016-05-31 Direct neural pathways convey distinct visual information to Drosophila mushroom bodies Vogt, Katrin Aso, Yoshinori Hige, Toshihide Knapek, Stephan Ichinose, Toshiharu Friedrich, Anja B Turner, Glenn C Rubin, Gerald M Tanimoto, Hiromu eLife Neuroscience Previously, we demonstrated that visual and olfactory associative memories of Drosophila share mushroom body (MB) circuits (Vogt et al., 2014). Unlike for odor representation, the MB circuit for visual information has not been characterized. Here, we show that a small subset of MB Kenyon cells (KCs) selectively responds to visual but not olfactory stimulation. The dendrites of these atypical KCs form a ventral accessory calyx (vAC), distinct from the main calyx that receives olfactory input. We identified two types of visual projection neurons (VPNs) directly connecting the optic lobes and the vAC. Strikingly, these VPNs are differentially required for visual memories of color and brightness. The segregation of visual and olfactory domains in the MB allows independent processing of distinct sensory memories and may be a conserved form of sensory representations among insects. DOI: http://dx.doi.org/10.7554/eLife.14009.001 eLife Sciences Publications, Ltd 2016-04-15 /pmc/articles/PMC4884080/ /pubmed/27083044 http://dx.doi.org/10.7554/eLife.14009 Text en © 2016, Vogt et al http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Vogt, Katrin
Aso, Yoshinori
Hige, Toshihide
Knapek, Stephan
Ichinose, Toshiharu
Friedrich, Anja B
Turner, Glenn C
Rubin, Gerald M
Tanimoto, Hiromu
Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
title Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
title_full Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
title_fullStr Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
title_full_unstemmed Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
title_short Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
title_sort direct neural pathways convey distinct visual information to drosophila mushroom bodies
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884080/
https://www.ncbi.nlm.nih.gov/pubmed/27083044
http://dx.doi.org/10.7554/eLife.14009
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