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Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals

Hedgehog signaling plays very important roles in development and cancers. Vertebrates have three transcriptional factors, Gli1, Gli2 and Gli3. Among them, Gli3 is a very special transcriptional factor which closely resembles Cubitus interruptus (Ci, in Drosophila) structurally and functionally as a...

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Detalles Bibliográficos
Autores principales:	Fu, Lin, Wu, Hailong, Cheng, Steven Y, Gao, Daming, Zhang, Lei, Zhao, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884081/ https://www.ncbi.nlm.nih.gov/pubmed/27146893 http://dx.doi.org/10.7554/eLife.15690

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