Oncogenic mTOR signaling recruits myeloid-derived suppressor cells to promote tumor initiation

Myeloid-derived suppressor cells (MDSCs) play critical roles in primary and metastatic cancer progression. While MDSC regulation is widely variable even within patients harboring the same type of malignancy, the mechanisms governing such heterogeneity are largely unknown. Here, integrating human tum...

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Detalles Bibliográficos
Autores principales: Welte, Thomas, Kim, Ik Sun, Tian, Lin, Gao, Xia, Wang, Hai, Li, June, Holdman, Xue B., Herschkowitz, Jason I., Pond, Adam, Xie, Guorui, Kurley, Sarah, Nguyen, Tuan, Liao, Lan, Dobrolecki, Lacey E., Mo, Qianxing, Edwards, Dean P., Huang, Shixia, Xin, Li, Xu, Jianming, Li, Yi, Lewis, Michael T., Wang, Tian, Westbrook, Thomas F., Rosen, Jeffrey M., Zhang, Xiang H.-F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884142/
https://www.ncbi.nlm.nih.gov/pubmed/27183469
http://dx.doi.org/10.1038/ncb3355

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