Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

To compare lung adenocarcinoma (ADC) and lung squamous cell carcinoma (SqCC) and to identify new drivers of lung carcinogenesis, we examined exome sequences and copy number profiles of 660 lung ADC and 484 lung SqCC tumor/normal pairs. Recurrent alterations in lung SqCCs were more similar to other s...

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Detalles Bibliográficos
Autores principales: Campbell, Joshua D., Alexandrov, Anton, Kim, Jaegil, Wala, Jeremiah, Berger, Alice H., Pedamallu, Chandra Sekhar, Shukla, Sachet A., Guo, Guangwu, Brooks, Angela N., Murray, Bradley A., Imielinski, Marcin, Hu, Xin, Ling, Shiyun, Akbani, Rehan, Rosenberg, Mara, Cibulskis, Carrie, Ramachandran, Aruna, Collisson, Eric A., Kwiatkowski, David J., Lawrence, Michael S., Weinstein, John N., Verhaak, Roel G. W., Wu, Catherine J., Hammerman, Peter S., Cherniack, Andrew D., Getz, Gad, Artyomov, Maxim N., Schreiber, Robert, Govindan, Ramaswamy, Meyerson, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884143/
https://www.ncbi.nlm.nih.gov/pubmed/27158780
http://dx.doi.org/10.1038/ng.3564

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