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Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy

Modulating immune inhibitory pathways has been a major recent breakthrough in cancer treatment. Checkpoint blockade antibodies targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programed cell-death protein 1 (PD-1) have demonstrated acceptable toxicity, promising clinical responses, durable di...

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Detalles Bibliográficos
Autores principales:	Ma, Weijie, Gilligan, Barbara M., Yuan, Jianda, Li, Tianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884396/ https://www.ncbi.nlm.nih.gov/pubmed/27234522 http://dx.doi.org/10.1186/s13045-016-0277-y

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