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Adaptations to chronic rapamycin in mice
Rapamycin inhibits mechanistic (or mammalian) target of rapamycin (mTOR) that promotes protein production in cells by facilitating ribosome biogenesis (RiBi) and eIF4E-mediated 5'cap mRNA translation. Chronic treatment with encapsulated rapamycin (eRapa) extended health and life span for wild-t...
Autores principales: | Dodds, Sherry G., Livi, Carolina B., Parihar, Manish, Hsu, Hang-Kai, Benavides, Adriana D., Morris, Jay, Javors, Martin, Strong, Randy, Christy, Barbara, Hasty, Paul, Sharp, Zelton Dave |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884683/ https://www.ncbi.nlm.nih.gov/pubmed/27237224 http://dx.doi.org/10.3402/pba.v6.31688 |
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