Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage

Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically...

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Detalles Bibliográficos
Autores principales: Boisen, Julie, Malone, C. Helen, Kelly, Brent, Wagner, Richard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884829/
https://www.ncbi.nlm.nih.gov/pubmed/27293916
http://dx.doi.org/10.1155/2016/9067428
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author Boisen, Julie
Malone, C. Helen
Kelly, Brent
Wagner, Richard F.
author_facet Boisen, Julie
Malone, C. Helen
Kelly, Brent
Wagner, Richard F.
author_sort Boisen, Julie
collection PubMed
description Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin.
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spelling pubmed-48848292016-06-12 Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage Boisen, Julie Malone, C. Helen Kelly, Brent Wagner, Richard F. Case Rep Dermatol Med Case Report Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin. Hindawi Publishing Corporation 2016 2016-05-16 /pmc/articles/PMC4884829/ /pubmed/27293916 http://dx.doi.org/10.1155/2016/9067428 Text en Copyright © 2016 Julie Boisen et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Boisen, Julie
Malone, C. Helen
Kelly, Brent
Wagner, Richard F.
Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_full Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_fullStr Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_full_unstemmed Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_short Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage
title_sort cutaneous squamous cell carcinoma with invasion through ear cartilage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884829/
https://www.ncbi.nlm.nih.gov/pubmed/27293916
http://dx.doi.org/10.1155/2016/9067428
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AT wagnerrichardf cutaneoussquamouscellcarcinomawithinvasionthroughearcartilage

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