Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells

The clinical promise of cancer immunotherapy relies on the premise that the immune system can recognize and eliminate tumor cells identified as non-self. However, tumors can evade host immune surveillance through multiple mechanisms, including epigenetic silencing of genes involved in antigen proces...

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Detalles Bibliográficos
Autores principales: Gameiro, Sofia R., Malamas, Anthony S., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884926/
https://www.ncbi.nlm.nih.gov/pubmed/26862729
http://dx.doi.org/10.18632/oncotarget.7180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884926/
https://www.ncbi.nlm.nih.gov/pubmed/26862729
http://dx.doi.org/10.18632/oncotarget.7180

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