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Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells
The clinical promise of cancer immunotherapy relies on the premise that the immune system can recognize and eliminate tumor cells identified as non-self. However, tumors can evade host immune surveillance through multiple mechanisms, including epigenetic silencing of genes involved in antigen proces...
Autores principales: | Gameiro, Sofia R., Malamas, Anthony S., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884926/ https://www.ncbi.nlm.nih.gov/pubmed/26862729 http://dx.doi.org/10.18632/oncotarget.7180 |
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