Proteomic discovery of MNT as a novel interacting partner of E3 ubiquitin ligase E6AP and a key mediator of myeloid differentiation

Perturbed stability of regulatory proteins is a major cause of transformations leading to cancer, including several leukemia subtypes. Here, for the first time we demonstrate that E6-associated protein (E6AP), an E3 ubiquitin ligase negatively targets MAX binding protein MNT for ubiquitin-mediated p...

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Detalles Bibliográficos
Autores principales: Kapoor, Isha, Kanaujiya, Jitendra, Kumar, Yogesh, Thota, Jagadeshwar Reddy, Bhatt, Madan L.B., Chattopadhyay, Naibedya, Sanyal, Sabyasachi, Trivedi, Arun Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884944/
https://www.ncbi.nlm.nih.gov/pubmed/26506232
http://dx.doi.org/10.18632/oncotarget.6156

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