PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells

Pancreatic adenocarcinoma is currently the fourth leading cause for cancer-related mortality. Malignant progression of pancreatic cancer depends not only on rapid proliferation of tumor cells but also on increased cell motility. In this study, we showed that increased PHLPP expression significantly...

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Detalles Bibliográficos
Autores principales: Smith, Alena J., Wen, Yang-An, Stevens, Payton D., Liu, Jingpeng, Wang, Chi, Gao, Tianyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884955/
https://www.ncbi.nlm.nih.gov/pubmed/26760962
http://dx.doi.org/10.18632/oncotarget.6848

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