Cargando…

Deletions of multidrug resistance gene loci in breast cancer leads to the down-regulation of its expression and predict tumor response to neoadjuvant chemotherapy

Neoadjuvant chemotherapy (NAC) is intensively used for the treatment of primary breast cancer. In our previous studies, we reported that clinical tumor response to NAC is associated with the change of multidrug resistance (MDR) gene expression in tumors after chemotherapy. In this study we performed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Litviakov, Nikolai V., Cherdyntseva, Nadezhda V., Tsyganov, Matvey M., Slonimskaya, Elena M., Ibragimova, Marina K., Kazantseva, Polina V., Kzhyshkowska, Julia, Choinzonov, Eugeniy L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884957/ https://www.ncbi.nlm.nih.gov/pubmed/26799285 http://dx.doi.org/10.18632/oncotarget.6953

Ejemplares similares

Amplifications of Stemness Gene Loci—New Markers for the Determination of the Need for Neoadjuvant Chemotherapy for Patients with Breast Cancer. A Prospective Study
por: Litviakov, Nikolai V., et al.
Publicado: (2021)

Intratumoral morphological heterogeneity of breast cancer: neoadjuvant chemotherapy efficiency and multidrug resistance gene expression
por: Denisov, Evgeny V., et al.
Publicado: (2014)

Tumor-associated macrophages in human breast cancer produce new monocyte attracting and pro-angiogenic factor YKL-39 indicative for increased metastasis after neoadjuvant chemotherapy
por: Liu, Tengfei, et al.
Publicado: (2018)

Whole Transcriptome Analysis of Breast Cancer Tumors during Neoadjuvant Chemotherapy: Association with Hematogenous Metastasis
por: Ibragimova, Marina K., et al.
Publicado: (2022)

Amplifications of stemness genes and the capacity of breast tumors for metastasis
por: Litviakov, Nikolai, et al.
Publicado: (2020)

Amplification of Stem Genes: New Potential Metastatic Makers in Patients with an Early Form of Breast Cancer
por: Tsyganov, Matvey M., et al.
Publicado: (2019)

Tumour Stem Cells in Breast Cancer
por: Ibragimova, Marina, et al.
Publicado: (2022)

Molecular-Genetic Portrait of Breast Cancer with Triple Negative Phenotype
por: Ibragimova, Marina K., et al.
Publicado: (2021)

Human papillomavirus and prostate cancer: systematic review and meta-analysis
por: Tsydenova, Irina A., et al.
Publicado: (2023)

Organ-Specificity of Breast Cancer Metastasis
por: Ibragimova, Marina K., et al.
Publicado: (2023)

CNA Landscape of HER2-Negative Breast Cancer in Anthracycline-Based Neoadjuvant Chemotherapy Regimens
por: Ibragimova, M. K., et al.
Publicado: (2023)

DNA Copy Number Aberrations and Expression of ABC Transporter Genes in Breast Tumour: Correlation with the Effect of Neoadjuvant Chemotherapy and Prognosis of the Disease
por: Tsyganov, Matvey M., et al.
Publicado: (2022)

Predictive and Prognostic Significance of mRNA Expression and DNA Copies Aberrations of ERCC1, RRM1, TOP1, TOP2A, TUBB3, TYMS, and GSTP1 Genes in Patients with Breast Cancer
por: Tsyganov, Matvey M., et al.
Publicado: (2022)

DNA methylation markers panel can improve prediction of response to neoadjuvant chemotherapy in luminal B breast cancer
por: Sigin, Vladimir O., et al.
Publicado: (2020)

Tumor-Associated Macrophages in Human Breast, Colorectal, Lung, Ovarian and Prostate Cancers
por: Larionova, Irina, et al.
Publicado: (2020)

Personalized Prescription of Chemotherapy Based on Assessment of mRNA Expression of BRCA1, RRM1, ERCC1, TOP1, TOP2α, TUBβ3, TYMS, and GSTP1 Genes in Tumors Compared to Standard Chemotherapy in the Treatment of Non-Small-Cell Lung Cancer
por: Tsyganov, Matvey M., et al.
Publicado: (2022)

Determination of BRCAness Phenotype in Breast Tumors for the Appointment of Neoadjuvant Chemotherapy Based on Platinum and Taxanes
por: Tsyganov, Matvey Mihajlovich, et al.
Publicado: (2022)

Phenotypic Drift as a Cause for Intratumoral Morphological Heterogeneity of Invasive Ductal Breast Carcinoma Not Otherwise Specified
por: Zavyalova, Marina V., et al.
Publicado: (2013)

Abscopal effect in the radio and immunotherapy
por: Pevzner, Alina M., et al.
Publicado: (2021)

Mutations of BRCA1, BRCA2, and PALB2 Genes in Breast Tumor Tissue: Relationship with the Effectiveness of Neoadjuvant Chemotherapy and Disease Prognosis
por: Tsyganov, Matvey M., et al.
Publicado: (2023)

Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF
por: Larionova, Irina, et al.
Publicado: (2023)

DNA Methylation and Prospects for Predicting the Therapeutic Effect of Neoadjuvant Chemotherapy for Triple-Negative and Luminal B Breast Cancer
por: Sigin, Vladimir O., et al.
Publicado: (2023)

Human Papillomavirus in Non-Small Cell Lung Carcinoma: Assessing Virus Presence in Tumor and Normal Tissues and Its Clinical Relevance
por: Tsyganov, Matvey M., et al.
Publicado: (2023)

WNT-Conditioned Mechanism of Exit from Postchemotherapy Shock of Differentiated Tumour Cells
por: Tsydenova, Irina A., et al.
Publicado: (2023)

Monocytes and Macrophages as Viral Targets and Reservoirs
por: Nikitina, Ekaterina, et al.
Publicado: (2018)

Interaction of tumor-associated macrophages and cancer chemotherapy
por: Larionova, Irina, et al.
Publicado: (2019)

Mechanisms behind prometastatic changes induced by neoadjuvant chemotherapy in the breast cancer microenvironment
por: Perelmuter, Vladimir M, et al.
Publicado: (2019)

Monocyte programming by cancer therapy
por: Patysheva, Marina, et al.
Publicado: (2022)

Intratumoral Morphological Heterogeneity of Breast Cancer As an Indicator of the Metastatic Potential and Tumor Chemosensitivity
por: Gerashchenko, T.S., et al.
Publicado: (2017)

Molecular subtype conversion in CTCs as indicator of treatment adequacy associated with metastasis-free survival in breast cancer
por: Grigoryeva, E. S., et al.
Publicado: (2022)

Heterogeneity of Circulating Tumor Cells in Neoadjuvant Chemotherapy of Breast Cancer
por: Kaigorodova, Evgeniya V., et al.
Publicado: (2018)

Aberrant Methylation of LINE-1 Transposable Elements: A Search for Cancer Biomarkers
por: Ponomaryova, Anastasia A., et al.
Publicado: (2020)

MALAT1 Long Non-coding RNA and Its Role in Breast Carcinogenesis
por: Tsyganov, M. M., et al.
Publicado: (2023)

Angiogenesis regulators S100A4, SPARC and SPP1 correlate with macrophage infiltration and are prognostic biomarkers in colon and rectal cancers
por: Kazakova, Elena, et al.
Publicado: (2023)

Involvement of Multidrug Resistance Modulators in the Regulation of the Mitochondrial Permeability Transition Pore
por: Fedotcheva, Tatiana, et al.
Publicado: (2022)

Markers of Cancer Cell Invasion: Are They Good Enough?
por: Gerashchenko, Tatiana S., et al.
Publicado: (2019)

Effect of Early-Stage Human Breast Carcinoma on Monocyte Programming
por: Patysheva, Marina, et al.
Publicado: (2022)

Unlocking the Viral Universe: Metagenomic Analysis of Bat Samples Using Next-Generation Sequencing
por: Roev, German V., et al.
Publicado: (2023)

PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse
por: Larionova, Irina, et al.
Publicado: (2023)

Expression of genes involved in carbohydrate‐lipid metabolism in muscle and fat tissues in the initial stage of adult‐age obesity in fed and fasted mice
por: Bazhan, Nadezhda M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i2tc3jdr8s7m1f0jd8a0phjrh0