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Inhibition of breast cancer cell motility with a non-cyclooxygenase inhibitory derivative of sulindac by suppressing TGFβ/miR-21 signaling

Compelling efficacy on intervention of tumorigenesis by nonsteroidal anti-inflammatory drugs (NSAIDs) has been documented intensively. However, the toxicities related to cyclooxygenase (COX) inhibition resulting in suppression of physiologically important prostaglandins limit their clinical use for...

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Detalles Bibliográficos
Autores principales: Yi, Bin, Chang, Hong, Ma, Ruixia, Feng, Xiangling, Li, Wei, Piazza, Gary A., Xi, Yaguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884969/
https://www.ncbi.nlm.nih.gov/pubmed/26769851
http://dx.doi.org/10.18632/oncotarget.6888