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Patient-derived xenograft (PDX) tumors increase growth rate with time
Patient-derived xenograft (PDX) models are frequently used for translational cancer research, and are assumed to behave consistently as the tumor ages. However, growth rate constancy as a function of time is unclear. Notably, variable PDX growth rates over time might have implications for the interp...
Autores principales: | Pearson, Alexander T., Finkel, Kelsey A., Warner, Kristy A., Nör, Felipe, Tice, David, Martins, Manoela D., Jackson, Trachette L., Nör, Jacques E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884970/ https://www.ncbi.nlm.nih.gov/pubmed/26783960 http://dx.doi.org/10.18632/oncotarget.6919 |
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