Ovatodiolide Inhibits Breast Cancer Stem/Progenitor Cells through SMURF2-Mediated Downregulation of Hsp27

Cancer stem/progenitor cells (CSCs) are a subpopulation of cancer cells involved in tumor initiation, resistance to therapy and metastasis. Targeting CSCs has been considered as the key for successful cancer therapy. Ovatodiolide (Ova) is a macrocyclic diterpenoid compound isolated from Anisomeles i...

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Detalles Bibliográficos
Autores principales: Lu, Kuan-Ta, Wang, Bing-Yen, Chi, Wan-Yu, Chang-Chien, Ju, Yang, Jiann-Jou, Lee, Hsueh-Te, Tzeng, Yew-Min, Chang, Wen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885042/
https://www.ncbi.nlm.nih.gov/pubmed/27136586
http://dx.doi.org/10.3390/toxins8050127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885042/
https://www.ncbi.nlm.nih.gov/pubmed/27136586
http://dx.doi.org/10.3390/toxins8050127

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