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Ovatodiolide Inhibits Breast Cancer Stem/Progenitor Cells through SMURF2-Mediated Downregulation of Hsp27

Cancer stem/progenitor cells (CSCs) are a subpopulation of cancer cells involved in tumor initiation, resistance to therapy and metastasis. Targeting CSCs has been considered as the key for successful cancer therapy. Ovatodiolide (Ova) is a macrocyclic diterpenoid compound isolated from Anisomeles i...

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Detalles Bibliográficos
Autores principales:	Lu, Kuan-Ta, Wang, Bing-Yen, Chi, Wan-Yu, Chang-Chien, Ju, Yang, Jiann-Jou, Lee, Hsueh-Te, Tzeng, Yew-Min, Chang, Wen-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885042/ https://www.ncbi.nlm.nih.gov/pubmed/27136586 http://dx.doi.org/10.3390/toxins8050127

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