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New Insights into VacA Intoxication Mediated through Its Cell Surface Receptors

Helicobacter pylori (H. pylori), a major cause of gastroduodenal diseases, produces VacA, a vacuolating cytotoxin associated with gastric inflammation and ulceration. The C-terminal domain of VacA plays a crucial role in receptor recognition on target cells. We have previously identified three prote...

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Detalles Bibliográficos
Autores principales: Yahiro, Kinnosuke, Hirayama, Toshiya, Moss, Joel, Noda, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885067/
https://www.ncbi.nlm.nih.gov/pubmed/27187473
http://dx.doi.org/10.3390/toxins8050152