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Structure–Activity Relationship for the 4(3H)-Quinazolinone Antibacterials
[Image: see text] We recently reported on the discovery of a novel antibacterial (2) with a 4(3H)-quinazolinone core. This discovery was made by in silico screening of 1.2 million compounds for binding to a penicillin-binding protein and the subsequent demonstration of antibacterial activity against...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885108/ https://www.ncbi.nlm.nih.gov/pubmed/27088777 http://dx.doi.org/10.1021/acs.jmedchem.6b00372 |