Lysophosphatidic acid receptors LPA(4) and LPA(6) differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

Naive lymphocytes continuously migrate from the blood into lymph nodes (LNs) via high endothelial venules (HEVs). To extravasate from the HEVs, lymphocytes undergo multiple adhesion steps, including tethering, rolling, firm adhesion and transmigration. We previously showed that autotaxin (ATX), an e...

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Detalles Bibliográficos
Autores principales: Hata, Erina, Sasaki, Naoko, Takeda, Akira, Tohya, Kazuo, Umemoto, Eiji, Akahoshi, Noriyuki, Ishii, Satoshi, Bando, Kana, Abe, Takaya, Kano, Kuniyuki, Aoki, Junken, Hayasaka, Haruko, Miyasaka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885216/
https://www.ncbi.nlm.nih.gov/pubmed/26714589
http://dx.doi.org/10.1093/intimm/dxv072

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