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Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation
Activation of G(s)-coupled receptors enhances engraftment of hematopoietic stem and progenitor cells (HSPCs). We tested the hypothesis that treprostinil, a prostacyclin analog approved for the treatment of pulmonary hypertension, can be repurposed to improve hematopoietic stem cell transplantation....
Autores principales: | Kazemi, Zahra, Bergmayr, Christian, Prchal-Murphy, Michaela, Javaheri, Tahereh, Themanns, Madeleine, Pham, Ha T. T., Strohmaier, Wolfgang, Sexl, Veronika, Freissmuth, Michael, Zebedin-Brandl, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885501/ https://www.ncbi.nlm.nih.gov/pubmed/26989084 http://dx.doi.org/10.1124/mol.116.103267 |
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