Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor

Activation of G protein-coupled receptors results in multiple waves of signaling that are mediated by heterotrimeric G proteins and the scaffolding proteins β-arrestin 1/2. Ligands can elicit full or subsets of cellular responses, a concept defined as ligand bias or functional selectivity. However,...

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Detalles Bibliográficos
Autores principales: Delgado-Peraza, Francheska, Ahn, Kwang H., Nogueras-Ortiz, Carlos, Mungrue, Imran N., Mackie, Ken, Kendall, Debra A., Yudowski, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885504/
https://www.ncbi.nlm.nih.gov/pubmed/27009233
http://dx.doi.org/10.1124/mol.115.103176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885504/
https://www.ncbi.nlm.nih.gov/pubmed/27009233
http://dx.doi.org/10.1124/mol.115.103176

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