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Increased Vagal Tone and Sleep Apnea Syndrome

It has been observed that atrial overdrive pacing abolishes sleep apnea syndrome, but how it does so has not been explained. There is a possibility that it sends a retrograde inhibitory impulse to the vagal center in the brainstem, which in turn reduces the vagal tone, and thus prevents sleep apnea....

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Detalles Bibliográficos
Autor principal: Ahmed, Tosaddak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal of Therapeutics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885585/
https://www.ncbi.nlm.nih.gov/pubmed/25933142
http://dx.doi.org/10.1097/MJT.0000000000000240
Descripción
Sumario:It has been observed that atrial overdrive pacing abolishes sleep apnea syndrome, but how it does so has not been explained. There is a possibility that it sends a retrograde inhibitory impulse to the vagal center in the brainstem, which in turn reduces the vagal tone, and thus prevents sleep apnea. Therefore, medical vagolytics such as atropine type of drugs should have the same effect. This is a case report of such an attempt.